Penn Med Antimicrobial Stewardship
Antimicrobial Stewardship Schedule: schedule of which pharmacist(s) and attending physicians are rotating on a given week at HUP
| Minor | ceftazidime |
|---|---|
| Critical | ceftazidime-avibactam1, primaquine, pentamidine, doxycycline IV, rifampin IV, tobramycin powder |
| Unavailable | cefotaxime, amphotericin B (deoxycholate only) |
1Ceftazidime-avibactam is unavailable due to a temporary shortage. We have a critically short supply. Providers should use alternative medications such as meropenem-vaborbactam when appropriate. Consult infectious diseases for additional advice.
- This website has been recently redesigned. Any suggestions/errors should be emailed to brian.chu@pennmedicine.upenn.edu.
- The health system has developed preliminary treatment guidance for patients diagnosed with SARS-CoV-2 (COVID-19) infection. We encourage you to check these guidelines frequently, as they may rapidly change based on new information.
- To get the ILÚM app, search and download on iTunes or GoogleTM Play. The app can be used to request antibiotic approval, perform predictive analytics, search guidelines, and see UPHS antibiograms. The same functionality is also available on the ILÚM website. TODO
- The antimicrobial stewardship team in partnership with nursing leadership at the Hospital of the University of Pennsylvania is implementing a nursing-managed allergy de-labeling intervention.
- Microbiology is now performing organism identification using the ePlex® system for Gram-positive organisms, which will provide faster organism identification and will also identify the presence or absence of certain resistance genes.
The prevalence of antimicrobial resistance is increasing at an alarming rate, placing critical importance on the preservation of available antimicrobial agents. Antimicrobial stewardship is a practice aimed at monitoring and guiding antimicrobial use in healthcare settings using evidence-based practices. It is known that approximately 50% of inpatient antimicrobial use is inappropriate, and there is a clear association between use of antimicrobials and development of resistance. Numerous studies and national guidelines have supported stewardship as an integral strategy to reduce emergence of antimicrobial resistance, improve patient outcomes, and decrease healthcare costs.rapidly change based on new information.
The goals of the antimicrobial stewardship team are to:
- Provide support to healthcare workers.
- Decrease inappropriate antimicrobial use.
- Optimize selection, dose, and duration of antimicrobial therapy.
- Streamline costs associated with antimicrobial use.
- Decrease spread and emergence of antimicrobial resistance.
- Improve patient outcomes.
Antimicrobial stewardship policy at the Hospital of the University of Pennyslvania